Autonomic nervous system activity correlates with peak experiences induced by DMT and predicts increases in well-being.

ABSTRACT:

Background

Non-ordinary states of consciousness induced by psychedelics can be accompanied by so-called "peak experiences," characterized at the emotional level by their intensity and positive valence. These experiences are strong predictors of positive outcomes following psychedelic-assisted therapy, and it is therefore important to better understand their biology. Despite growing evidence that the autonomic nervous system (ANS) plays an important role in mediating emotional experiences, its involvement in the psychedelic experience is poorly understood. The aim of this study was to investigate to what extent changes in the relative influence of the sympathetic (SNS) and parasympathetic nervous systems (PNS) over cardiac activity may reflect the subjective experience induced by th

SUBMITTER: Bonnelle V 

PROVIDER: S-EPMC11512487 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature