Surface-functionalized PAN fiber membranes for the sensitive detection of airborne specific markers.

ABSTRACT: PAN fibers are characterized by having a large surface-to-volume ratio and small pores, which are beneficial for applications in filtration and specific molecular detection systems. Naturally, larger items are filtered, and a lower ratio between specific and nonspecific binding is expected since small pores do not allow larger elements to penetrate through membranes; thus, nonspecific binding is enhanced. We prepared and tested fiber membranes (diameter cca 700 nm) functionalized with a specific antibody to prove that even microscopic systems such as bacteria could be specifically identified. In addition, we established a methodology that enabled the effective binding of bacteria in not only an aqueous environment but also air. Our data clearly prove that even large systems such as bacteri

SUBMITTER: Varvarovska L 

PROVIDER: S-EPMC11512550 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature