The relationship between glucose patterns in OGTT and adverse pregnancy outcomes in twin pregnancies.

ABSTRACT:

Background

Traditional fixed thresholds for oral glucose tolerance test (OGTT) results may inadequately prevent adverse pregnancy outcomes in twin pregnancies. This study explores latent OGTT patterns and their association with adverse outcomes.

Methods

This study retrospectively analyzed 2644 twin pregnancies using latent mixture models to identify glucose level patterns (high, HG; medium, MG; and low, LG) and their relationship with maternal/neonatal characteristics, gestational age at delivery, and adverse outcomes.

Results

Three distinct glucose patterns, HG, MG, and LG patterns were identified. Among the participants, 16.3% were categorized in the HG pattern. After adjustment, compared with the LG pattern, the HG pattern was associated with a 1.79-fold, 1.66-fold

SUBMITTER: Tang WZ 

PROVIDER: S-EPMC11513445 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature