Temporal and masseter muscle evaluation by MRI provides information on muscle mass and quality in acromegaly patients.

ABSTRACT:

Purpose

The impact of GH/IGF-1 levels on skeletal muscle in acromegaly is still controversial. Temporal (TMT) and masseter muscle (MMT) thickness has been recently demonstrated as a reliable measure of muscle mass. We aimed to investigate the relationship between TMT, MMT and clinical/biochemical characteristics in patients with acromegaly.

Methods

Single center retrospective longitudinal study including 69 patients with at least one available brain/sella turcica MRI and matched clinical data. TMT, MMT, and muscle fatty infiltration (modified Goutallier score) were evaluated in all patients at baseline (first available MRI) and over time (182 MRIs analyzed).

Results

At baseline, both TMT and MMT were higher in males than females (p = 0.001 and p = 0.016, respectively)

SUBMITTER: Gatto F 

PROVIDER: S-EPMC11513697 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature