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Hyponatremia as a predictor of complicated appendicitis: a systematic review and meta-analysis.


ABSTRACT: Aim: To investigate the value of hyponatremia as a predictive marker for complicated appendicitis.Methods: PubMed, Embase, Web of Science and Scopus databases were searched for studies published up to 5 June 2024. Studies reporting serum sodium levels in patients with complicated and non-complicated appendicitis and studies reporting the association between baseline hyponatremia and complicated appendicitis were included. A random-effects meta-analysis was performed.Results: Twenty-two studies met the eligibility criteria. Serum sodium levels were measured at arrival or preoperatively in all included studies. Meta-analysis of data from 17 studies showed that preoperative sodium levels were significantly lower in patients with complicated appendicitis vs uncomplicated a

SUBMITTER: Shi H 

PROVIDER: S-EPMC11514541 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature