Altered brainstem-cortex activation and interaction in migraine patients: somatosensory evoked EEG responses with machine learning.

ABSTRACT:

Background

To gain a comprehensive understanding of the altered sensory processing in patients with migraine, in this study, we developed an electroencephalography (EEG) protocol for examining brainstem and cortical responses to sensory stimulation. Furthermore, machine learning techniques were employed to identify neural signatures from evoked brainstem-cortex activation and their interactions, facilitating the identification of the presence and subtype of migraine.

Methods

This study analysed 1,000-epoch-averaged somatosensory evoked responses from 342 participants, comprising 113 healthy controls (HCs), 106 patients with chronic migraine (CM), and 123 patients with episodic migraine (EM). Activation amplitude and effective connectivity were obtained using weighted minimum

SUBMITTER: Hsiao FJ 

PROVIDER: S-EPMC11514809 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature