Effects of clear aligners and traditional removable appliances on oral microbiome in mixed dentition: a comparative study.

ABSTRACT:

Background

This prospective study aims to investigate the comparative effects of clear aligners (CA) and traditional removable appliances (RA) on the cariogenic risk of patients in mixed dentition, focusing on the oral microbiome.

Methods

25 children were included and assigned into CA and RA groups. Supragingival plaque and saliva samples were collected, and clinical parameters including Decay-missing-filled teeth index (DMFT), Plaque Index (PI) and Gorelick Index (GI) were recorded before treatment (T₀) and after 6-month follow-up (T₁). DNA was extracted from supragingival plaque and saliva and analyzed via 16S rDNA gene sequencing.

Results

Clinical parameters showed no statistically significant difference between groups at each time point or wi

SUBMITTER: Chen W 

PROVIDER: S-EPMC11515335 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature