Association between healthy lifestyle on life course and multimorbidity in adults: results from two national prospective cohort studies.

ABSTRACT:

Objectives

To examine the correlation between healthy lifestyle patterns, their change trajectories, and the risk of multimorbidity in adults.

Methods

Based on two representative national cohorts, the English Longitudinal Study of Aging (ELSA) and the Health and Retirement Study (HRS) including adults aged 50 years and over. We employed Cox regression, lifestyle change trajectories, and restricted mean survival times to explore the relationship between lifestyle (assessed by SCORE2, LE'8, and HLS scores) and multimorbidity. We also conducted mediation analysis to investigate the underlying mechanisms.

Results

A healthy lifestyle (higher LE'8, higher HLS, or lower SCORE2) can reduce the risk of multimorbidity. 2-10% lower multimorbidity risk per one-point increase in L

SUBMITTER: Ye X 

PROVIDER: S-EPMC11515530 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature