Six type-I PKS classes and highly conserved melanin and elsinochrome gene clusters found in diverse Elsinoe species.

ABSTRACT: Elsinoë species are phytopathogenic fungi that cause serious scab diseases on economically important plants. The disease symptoms arise from the effects of a group of phytotoxins known as elsinochromes, produced via a type-I polyketide synthase (PKS) biosynthetic pathway. The elsinochrome gene cluster was first annotated in Elsinoë fawcettii where the main type-I PKS gene was characterized as EfPKS1. A later study showed that this gene and the associated cluster had not been correctly annotated, and that EfPKS1 was actually the anchor gene of the melanin biosynthetic pathway. A new type-I PKS gene EfETB1 associated with elsinochrome production was also identified. The aim of this study was to identify all type-I PKS genes in the genomes of seven Elsinoë species with the goal of independent

SUBMITTER: van Heerden A 

PROVIDER: S-EPMC11515665 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature