What is the impact of acute endocrine and metabolic alterations on long-term ischemic stroke prognosis: a prospective study.

ABSTRACT:

Background

Post-stroke stress can trigger instant survival but its influence on long-term ischemic stroke outcomes remains controversial. Thus, we sought to explore the associations of acute post-stroke stress evidenced by endocrine and metabolic changes, with long-term ischemic stroke outcomes.

Methods

Admissions for acute ischemic stroke within seven days of onset were prospectively recruited to determine acute endocrine and metabolic variations measured by thyroid parameters and the stress hyperglycemia ratio (SHR). Long-term ischemic stroke prognoses were followed up for one year, with the primary outcome being a modified Rankin Scale score of 3 to 6.

Results

A total of 887 patients were enrolled, of which 535 reached the final one-year followed up at a poor progn

SUBMITTER: Pang C 

PROVIDER: S-EPMC11515757 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature