Combined effect of anion gap and red cell distribution width on the risk of acute kidney injury after cardiac surgery.

ABSTRACT:

Background

This study was to analyze the roles of red blood cell distribution width (RDW), anion gap (AG) levels and their combined effects on the risk of acute kidney injury (AKI) following cardiac surgery.

Methods

This cohort study extracted the data of 1951 participants aged ≥ 18 years with the assessment of AKI after cardiac surgery during ICU stay from MIMIC-IV database between 2008 and 2019. Receiver operator characteristic (ROC) curve was used to determine the optimal cut-off value AG and RDW. The associations between AG, RDW, and the combined effects of AG and effects were evaluated via univariable and multivariable Logistic models. Odds ratio (OR) with 95% confidence interval (CI) were imputed.

Results

Among all the participants, 831 participants had AKI, and

SUBMITTER: Zheng B 

PROVIDER: S-EPMC11515780 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature