Diagnostic criteria and core outcome set development for necrotising otitis externa: the COSNOE Delphi consensus study.

ABSTRACT:

Objective

Evidence for necrotising otitis externa (NOE) diagnosis and management is limited, and outcome reporting is heterogeneous. International best practice guidelines were used to develop consensus diagnostic criteria and a core outcome set (COS).

Methods

The study was pre-registered on the Core Outcome Measures in Effectiveness Trials (COMET) database. Systematic literature review identified candidate items. Patient-centred items were identified via a qualitative study. Items and their definitions were refined by multidisciplinary stakeholders in a two-round Delphi exercise and subsequent consensus meeting.

Results

The final COS incorporates 36 items within 12 themes: Signs and symptoms; Pain; Advanced Disease Indicators; Complications; Survival; Antibiotic regi

SUBMITTER: Lodhi S 

PROVIDER: S-EPMC11518678 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature