Using genetic variations to reveal the complex relationships between vegetarianism and well-being, depressive symptoms and neuroticism.

ABSTRACT:

Background

The relationship between vegetarianism and mental well-being remains a debated topic in traditional observational studies. Recent studies have revealed the genetic factors in vegetarianism. We aimed to use genetic variations to explore the potential causal relationships between vegetarianism and mental well-being, offering insights from a new perspective.

Methods

We conducted the inverse variance weighted approach as the primary analysis to explore the bidirectional genetic associations between vegetarianism (N = 442,589) and depressive symptoms (N = 180,866), neuroticism (N = 170,910), and subjective well-being (N = 298,420). The analysis used the summary data from the largest genome-wide association studies (GWAS). We also performed s

SUBMITTER: Chen K 

PROVIDER: S-EPMC11518772 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature