Nationwide usage of ethambutol and incidence and screening practices of optic neuropathy.

ABSTRACT:

Introduction

Ethambutol, a key anti-tuberculosis medication, is associated with optic neuropathy, which can lead to significant vision impairment. This population-based cohort study investigated the nationwide usage of ethambutol and the incidence and screening of optic neuropathy among ethambutol users.

Methods

The cohort included 206,157 individuals from the Health Insurance Review and Assessment database in South Korea who initiated ethambutol therapy between 1 January 2015, and 31 December 2021. Among them, 117,309 individuals without prior ophthalmic diseases were analyzed to investigate practice patterns. The timing of the baseline examinations (an ophthalmic examination immediately preceding [within 1 month] ethambutol initiation or the first ophthalmic assessment con

SUBMITTER: Kim J 

PROVIDER: S-EPMC11518835 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature