Optimising Paediatric HIV Treatment: Recent Developments and Future Directions.

ABSTRACT: Treatment options for children living with HIV have historically been less effective, less practical and more difficult to implement compared with those for adults, as the research and development of new drugs for children has lagged behind. Significant progress has been achieved in response to the paediatric HIV epidemic over the last decade. Several optimised paediatric antiretroviral formulations are currently available or in development, including fixed-dose combination tablets containing a complete World Health Organization-recommended regimen. Despite these advancements, virological suppression rates in children are generally lower than in adults. Even when oral fixed-dose combinations with the optimal target profiles are developed, for some children virological suppression is not ac

SUBMITTER: Kamphuis AEM 

PROVIDER: S-EPMC11519159 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature