Effect of roasted purple laver (nori) on vitamin B₁₂ nutritional status of vegetarians: a dose-response trial.

ABSTRACT:

Purpose

To investigate the bioavailability of vitamin B₁₂ from nori and to evaluate the required dosage for improving vitamin B₁₂ nutritional status in vegetarians not using supplements.

Methods

The study design is an open-label, parallel, dose-response randomized controlled trial. Thirty vegetarians were assigned to control (no nori), low-dose (5 g nori, aiming to provide 2.4 µg vitamin B₁₂ per day), or high-dose (8 g nori, aiming to provide 4 µg vitamin B₁₂ per day) groups. The primary outcome was changes in vitamin B₁₂ status as measured by serum vitamin B₁₂, holotranscobalamin (holoTC), homocysteine (Hcy), and methylmalonic acid (MMA), and a combined score of these four markers (4cB12 score) during the fou

SUBMITTER: Huang QN 

PROVIDER: S-EPMC11519184 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature