Management of hip osteoarthritis: harnessing the potential of mesenchymal stem cells-a systematic review.

ABSTRACT:

Introduction

Hip osteoarthritis (OA) is a prevalent and debilitating condition, necessitating effective and safe treatment options. This systematic review aims to explore the potential of intra-articular mesenchymal stem cell (MSC) infiltrations as a therapeutic approach for hip OA.

Methods

Following PRISMA guidelines, a systematic review was conducted, encompassing PubMed, Embase, and Cochrane Library databases. Inclusion criteria involved studies focusing on intra-articular MSC injections in patients with hip OA and reporting pain relief as an outcome measure. Quality assessment utilized the Newcastle-Ottawa scale and methodological index for non-randomized studies.

Results

Ten studies were included in the review, exhibiting varied designs and sample sizes (316 pati

SUBMITTER: Giorgino R 

PROVIDER: S-EPMC11519189 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature