Association between cognitive functioning and health-related quality of life and its mediation by depressive symptoms in older patients with kidney failure.

ABSTRACT:

Background

Impaired cognition, poor health-related quality of life (HRQoL) and depressive symptoms are common in older patients with kidney failure. Understanding what influences HRQoL is important, as older patients regard HRQoL as a health priority. This study examines whether cognitive functioning is associated with HRQoL and whether depressive symptoms mediate this effect in older patients with kidney failure.

Methods

Outpatients aged ≥ 65 years from 35 Dutch and Belgian hospitals with eGFR 20-10 mL/min/1.73 m² were included from the ongoing DIALOGICA study. Cognitive functioning was assessed using the Montreal Cognitive Assessment. Depressive symptoms were screened with 2 Whooley Questions and thereafter assessed with the 15-item Geriatric Depression Scale. H

SUBMITTER: Demirhan I 

PROVIDER: S-EPMC11519205 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature