The role of molecular subtypes and immune infiltration characteristics based on disulfidptosis-related genes in ovarian cancer.

ABSTRACT: Ovarian cancer (OC) is the most fatal, gynecological malignancy. Compared with advanced ovarian cancer, the 5 year survival rate of early ovarian cancer is significantly improved, and predicting early detection and diagnosis is very important to improve the prognosis of OC. Recent research has found a new way of cell death: disulfidptosis. Under glucose starvation, abnormal accumulation of disulfide molecules such as Cystine in SLC7A11 overexpression cells induced disulfide stress to trigger cell death. Studies of disulfidptosis are still in their infancy and its role in ovarian cancer progression is unclear. In this study, we used a public database to detect the expression and mutations of disulfidptosis-related genes in OC. Cluster analysis was performed based on disulfidptosis-related g

SUBMITTER: Yang R 

PROVIDER: S-EPMC11519262 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature