Design and synthesis of quorum-sensing agonist for improving biofilm formation and the application of Acidithiobacillus thiooxidans in bioleaching.

ABSTRACT:

Introduction

Currently, there are few investigations on the effect of a synthetic exogenous quorum sensing (QS) agonist on the bioleaching rate of Acidithiobacillus thiooxidans (A. thiooxidans).

Methods

We created AHL (N-acyl-homoserine lactone) analogues and investigated their effects on A. thiooxidans biofilm formation, adsorption kinetics, bioleaching, and mechanism.

Results

The findings revealed that N-(3-thiolactone)- dodecylamine (Y3) significantly increased the biofilm formation of A. thiooxidans in 96-well plates and sulfur sheets. Adsorption tests revealed that Y3 increased the adhesion rate, adsorption constant, and adsorption efficiency. Bioleaching tests indicated that Y3 boosted bioleaching efficiency, with Ni²⁺ and

SUBMITTER: Tang D 

PROVIDER: S-EPMC11519741 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature