Association between albumin-corrected anion gap and kidney function in individuals with hypertension - NHANES 2009-2016 cycle.

ABSTRACT:

Objectives

Long-term uncontrolled hypertension increases the risk of kidney decompensation. This study aimed to explore the connection between albumin-corrected anion gap (ACAG) and kidney function in hypertensive patients.

Methods

This study utilized data from 1988 participants diagnosed with hypertension sourced from the NHANES database. Binary logistic regression analysis and subgroup analysis were utilized to investigate the relationship between ACAG and kidney function. The study employed restricted cubic spline (RCS) to assess the non-linear associations between ACAG and eGFR, as well as ACAG and ACR. Furthermore, mediation and moderation effect analyses were carried out, with blood pressure serving as the mediator and moderator, ACAG as the independent variable, and e

SUBMITTER: Jiang H 

PROVIDER: S-EPMC11520097 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature