Optimal fluid resuscitation targets in septic patients with acutely decompensated heart failure.

ABSTRACT:

Background

To determine the optimal fluid resuscitation volume in septic patients with acutely decompensated heart failure (ADHF).

Methods

Septic patients with ADHF were identified from a tertiary urban medical center. The generalized additive models were used to explore the association between fluid resuscitation volume and endpoints, and the initial 3 h fluid resuscitation volume was divided into four groups according to this model: < 10 mL/kg group, ≥ 10 to ≤ 15 mL/kg group, > 15 to ≤ 20 mL/kg group, and > 20 mL/kg group. Logistic and Cox regression models were employed to explore the association between resuscitation volume and primary endpoint, in-hospital mortality, as well as secondary endpoints including 30-day mortality, 1-year mortality, invasive ventilation, and I

SUBMITTER: Weng J 

PROVIDER: S-EPMC11520127 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature