Adiposity and Muscle Strength in Men With Prostate Cancer and Cardiovascular Outcomes.

ABSTRACT:

Background

There are limited data on the physical effects of androgen deprivation therapy (ADT) for prostate cancer (PC), and on the relationships of such measures of adiposity and strength to cardiovascular outcomes.

Objectives

The primary objective of this study was to evaluate the relationships of measures of adiposity and strength to cardiovascular outcomes (cardiovascular death, myocardial infarction, stroke, heart failure, arterial revascularization, peripheral arterial disease, and venous thromboembolism) in patients with PC. A secondary objective was to characterize the relationships between ADT use and 12-month changes in these physical measures.

Methods

This international, prospective cohort study included 3,967 patients with PC diagnosed in the prior 12 mon

SUBMITTER: Leong DP 

PROVIDER: S-EPMC11520207 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature