Life's Essential 8 and Incident Cardiovascular Disease in U.S. Women With Breast Cancer.

ABSTRACT:

Background

Relationships between lifestyle risk factors and cardiovascular disease (CVD) risk in women with breast cancer (BC) are underexplored.

Objectives

To evaluate the incidence of CVD in relation to the Life's Essential 8 (LE8) score among women with BC.

Methods

Data from the Women's Health Initiative were utilized. The primary exposure was the LE8 score assessed prior to BC diagnosis. The LE8 score was stratified into low (0-59), moderate (60-79), and high (80-100) cardiovascular health (CVH). The primary endpoint was a composite of incident CVD events, which included coronary heart disease, defined as myocardial infarction along with coronary revascularization, CVD death, and stroke. We calculated the cumulative incidence of CVD and estimated hazard ratios.

SUBMITTER: Wadden E 

PROVIDER: S-EPMC11520208 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature