Growth-phase-dependent control of rRNA synthesis in Saccharomyces cerevisiae.

ABSTRACT: Saccharomyces cerevisiae is one of the most well-studied model organisms used in the scientific community. Its ease of manipulation, accessible growth conditions, short life cycle, and conserved eukaryotic metabolic pathways make it a useful model organism. Consequently, yeast has been used to investigate a myriad of phenomena, from microbial to human studies. Most of the research performed using this model organism utilizes yeast cell populations when they are growing exponentially, a growth phase aptly termed exponential or log phase. However, log phase encompasses several yeast generations and ranges several hours of yeast growth, meaning that there is a potential for variability during this "homogenous" growth phase. Cells in log phase require robust ribosome biogenesis to suppo

SUBMITTER: Mendes Felgueira CA 

PROVIDER: S-EPMC11520348 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature