Ashbya gossypii as a versatile platform to produce sabinene from agro-industrial wastes.

ABSTRACT:

Background

Ashbya gossypii is a filamentous fungus widely utilized for industrial riboflavin production and has a great potential as a microbial chassis for synthesizing other valuable metabolites such as folates, biolipids, and limonene. Engineered strains of A. gossypii can effectively use various waste streams, including xylose-rich feedstocks. Notably, A. gossypii has been identified as a proficient biocatalyst for producing limonene from xylose-rich sources. This study aims to investigate the capability of engineered A. gossypii strains to produce various plant monoterpenes using agro-industrial waste as carbon sources.

Results

We overexpressed heterologous terpene synthases to produce acyclic, monocyclic, and bicyclic monoterpenes in two genetic backgrounds of A. gossy

SUBMITTER: Munoz-Fernandez G 

PROVIDER: S-EPMC11520522 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature