Management and outcomes in pulmonary arterial hypertension patients with sepsis.

ABSTRACT:

Background

Sepsis is a common cause of death in patients with pulmonary arterial hypertension (PAH). Treatment requires careful fluid management and hemodynamic support. This study compares patients with or without PAH presenting with sepsis with a focus on initial fluid resuscitation.

Methods

This retrospective analysis compared adults with and without PAH admitted for sepsis at two academic hospitals between 2013 and 2022. Prior PAH diagnosis was verified by review of right heart catheterization data and sepsis present on admission was verified by chart review. Demographics, vital signs, laboratory values, imaging results, treatment approaches, and all-cause mortality data were obtained. Controls were propensity score weighted by age, sex, and Charlson Comorbidity index. L

SUBMITTER: Flynn S 

PROVIDER: S-EPMC11520816 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature