Age-dependent immune profile in healthy individuals: an original study, systematic review and meta-analysis.

ABSTRACT:

Background

The circulatory peripheral immune system is the most convenient approach for determining an individual's immune status. Due to various reasons, while previous studies have addressed the critical impact of age, most individual studies did not analyze immunosenescence in a systemic manner, which complicates the possibility of building a reference range for age-dependent immune profiles for effective immune monitoring. To address this gap, this study analyzed a group of healthy individuals to establish age-specific reference ranges of the healthy circulatory immune profile, and a systematic review and meta-analysis were conducted to validate the findings and create generalizable immune cell reference ranges.

Results

Our study recruited a total of 363 healthy Taiwanes

SUBMITTER: Chang ST 

PROVIDER: S-EPMC11520839 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature