Mueller matrix analysis of a biologically sourced engineered tissue construct as polarimetric phantom.

ABSTRACT:

Significance

The polarimetric properties of biological tissues are often difficult to ascertain independent of their complex structural and organizational features. Conventional polarimetric tissue phantoms have well-characterized optical properties but are overly simplified. We demonstrate that an innovative, biologically sourced, engineered tissue construct better recapitulates the desired structural and polarimetric properties of native collagenous tissues, with the added benefit of potential tunability of the polarimetric response. We bridge the gap between non-biological polarimetric phantoms and native tissues.

Aim

We aim to evaluate a synthesized tissue construct for its effectiveness as a phantom that mimics the polarimetric properties in typical collagenous tissues.

SUBMITTER: Lin Z 

PROVIDER: S-EPMC11521148 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature