NF2-Related Schwannomatosis Exhibiting the Complete Constellation of Multiple Inherited Schwannomas, Meningiomas, and Ependymomas (MISME Syndrome).

ABSTRACT:

Introduction

NF2-related schwannomatosis (NF2) is a rare inheritable autosomal dominant disorder characterized by multiple nervous system neoplasms.

Case presentation

In this report, we present a rare case of NF2 exhibiting the complete constellation of multiple inherited schwannomas, meningiomas, and ependymomas (MISME syndrome).

Conclusion

This is the first documented case of simultaneous occurrence of all three tumors in a single patient in the Philippines, adding to the sparse evidence of MISME syndrome in world literature.

SUBMITTER: Pedregosa B 

PROVIDER: S-EPMC11521411 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature