Cerebrospinal Fluid Leak and Idiopathic Intracranial Hypertension in a Transgender Male: Is Intracranial Hypertension Hormonally Mediated?

ABSTRACT:

Introduction

The pathophysiology of idiopathic intracranial hypertension (IIH) is not fully characterized, and less is known about its development in transgender patients. Several cases of IIH in transgender patients have been reported, but fewer cases have been published that identify a cerebrospinal fluid (CSF) leak as a complication of IIH in this population. These patients can serve as an important study population, as an association between exogenous testosterone use in karyotypical females and development of IIH may support a hormonally mediated mechanism of development of this disease.

Case presentation

We describe the case of a 33-year-old obese (BMI: 30.58 kg/m²) female-to-male transgender patient on exogenous testosterone for 15 years who presented with

SUBMITTER: Smith I 

PROVIDER: S-EPMC11521422 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature