Treatment of a Complex Case of Scleromyxedema Using a Novel Intravenous Immunoglobulin Preparation.

ABSTRACT:

Introduction

We provide a case report on a patient with scleromyxedema treated with high-dose intravenous immunoglobulins (IVIgs) who reported less fatigue and fewer headaches after transitioning to Yimmugo, a novel IVIg preparation. Scleromyxedema is a rare and chronic cutaneous mucinosis, frequently associated with monoclonal gammopathy and systemic complications, which may be life-threatening. The disease is characterized by papular eruptions and sclerosis of the skin. Treatment of scleromyxedema is challenging because of its unclear pathogenesis. High-dose IVIgs are a promising treatment option to improve cutaneous manifestations.

Case presentation

We present the case of a 57-year-old patient with scleromyxedema and monoclonal gammopathy with end-stage renal failure on h

SUBMITTER: Vollmer AS 

PROVIDER: S-EPMC11521433 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature