Purpura Fulminans from <i>Capnocytophaga canimorsus</i> in an Immunocompromised Host.

ABSTRACT:

Introduction

Purpura fulminans is a rare but fatal manifestation of Capnocytophaga canimorsus bacteremia that can present in immunocompromised hosts. This can have a profound impact on patients, including recipients of allogeneic hematopoietic stem cell transplant. Despite aggressive therapy, mortality can be as high as 60% and most patients require amputation of multiple extremities.

Case presentation

We present a 31-year-old woman s/p myeloablative allogeneic transplant, presenting with purpura fulminans and septic shock. She had been on Immunosuppressive therapy with rituximab and tacrolimus. Despite aggressive antibiotic coverage and supportive therapy, although her shock was resuscitated, she had to undergo bilateral below-knee amputations.

Discussion

We a

SUBMITTER: Varadarajan I 

PROVIDER: S-EPMC11521502 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature