Neurodevelopmental outcomes in children prenatally exposed to opioid maintenance treatment: A population-based study.

ABSTRACT:

Background and objectives

Opioid maintenance treatment (OMT), with methadone or buprenorphine, is a key approach for managing opioid use disorder (OUD) during pregnancy. Despite buprenorphine's superior short-term outcomes, its long-term effects remain understudied. This study aims to evaluate the effects of prenatal OMT exposure on the incidence of childhood neurodevelopmental disorders (NDDs) considering timing effect.

Methods

A retrospective cohort study using Rhode Island Medicaid data linked to vital statistics from 2008 to 2018 was conducted. The study included pregnancies having live birth from 2008 to 2016 with continuous Medicaid insurance and OUD diagnosis within 3 months preceding conception until delivery. At least one buprenorphine dispensing or a claim of metha

SUBMITTER: Hasan M 

PROVIDER: S-EPMC11521574 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature