Studying Pregnancy Outcome Risk in Patients with Systemic Lupus Erythematosus Based on Cluster Analysis.

ABSTRACT:

Background

Pregnancy in systemic lupus erythematosus (SLE) patients is a challenge due to the potential maternal and fetal complications. Therefore, a multidisciplinary assessment of disease risk before and during pregnancy is essential to improve pregnancy outcomes.

Objectives

Our purpose was to (i) define clusters of patients with similar history and laboratory features and determine the associative maternal and perinatal outcomes and (ii) evaluate the risk spectrum of maternal and perinatal outcomes of pregnancy in SLE patients, represented by our established risk-assessment chart.

Methods

Medical records of 119 patients in China were analyzed retrospectively. Significant variables with p < 0.05 were selected. The self-organizing map was used for clustering

SUBMITTER: Bikdeli A 

PROVIDER: S-EPMC11521590 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature