Bipolar and Laplacian montages are suitable for high-gamma modulation language mapping with stereoelectroencephalography.

ABSTRACT:

Objective

To determine the optimal montage and vocalization conditions for high-gamma language mapping using stereoelectroencephalography.

Methods

We studied 12 epilepsy patients who underwent invasive monitoring with depth electrodes and measurement of auditory-naming related high-gamma modulations. We determined the effects of electrode montage and vocalization conditions of the response on the high-gamma (60-140 Hz) amplitudes.

Results

Compared to common average reference montage, bipolar and Laplacian montages effectively reduced the degree of auditory naming-related signal deflections in the white matter during the stimulus and response phases (mixed model estimate: -21.2 to -85.4%; p < 0.001), while maintaining those at the cortical level (-4.4 to +7.8%;

SUBMITTER: Mitsuhashi T 

PROVIDER: S-EPMC11521834 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature