Association of serum intact parathyroid hormone levels with sarcopenia in patients undergoing peritoneal dialysis.

ABSTRACT:

Objective

Sarcopenia is highly prevalent in patients undergoing peritoneal dialysis (PD), contributing to adverse clinical outcomes. Animal models suggest that parathyroid hormone (PTH) induces muscle wasting through adipose tissue browning. However, the relationship between PTH dysregulation and sarcopenia in the PD population remains unclear. Thus, we aimed to explore the association between serum intact PTH levels and sarcopenia in PD patients.

Methods

We conducted a cross-sectional analysis using data from the Tzu-Chi PD cohort, comprising 186 PD patients with a mean age of 57.5 ± 14.1 years. Basic information, comorbidities, serum intact PTH levels, and other biochemical data were retrieved. Atherosclerotic cardiovascular disease (ASCVD) includes any history of coronary

SUBMITTER: Hsu BG 

PROVIDER: S-EPMC11521897 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature