Modeling and characterization of pure and odorant mixture processing in the <i>Drosophila</i> mushroom body calyx.

ABSTRACT: Associative memory in the Mushroom Body of the fruit fly brain depends on the encoding and processing of odorants in the first three stages of the Early Olfactory System: the Antenna, the Antennal Lobe and the Mushroom Body Calyx. The Kenyon Cells (KCs) of the Calyx provide the Mushroom Body compartments the identity of pure and odorant mixtures encoded as a train of spikes. Characterizing the code underlying the KC spike trains is a major challenge in neuroscience. To address this challenge we start by explicitly modeling the space of odorants using constructs of both semantic and syntactic information. Odorant semantics concerns the identity of odorants while odorant syntactics pertains to their concentration amplitude. These odorant attributes are multiplicatively coupled in the process

SUBMITTER: Lazar AA 

PROVIDER: S-EPMC11521939 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature