Metabolic obesity phenotypes and the risk of cancer: a prospective study of the Kailuan cohort.

ABSTRACT:

Background

Obesity is as an important risk factor for chronic diseases. Metabolically healthy obesity (MHO) is considered a benign state. The association between metabolic health and obesity categories and cancer risk remains unclear. This study aimed to investigate the relationship between metabolic health status combined with obesity phenotypes and the risk of cancer.

Methods

Data from 91,834 participants in the Kailuan cohort were analyzed, excluding individuals with a body mass index (BMI) < 18.5 kg/m² and those with a history of cancer. Obesity phenotypes were classified based on BMI and waist circumference (WC) combined with metabolic health status, resulting in six phenotypes. Cox proportional hazard regression models were used to assess the association between metabo

SUBMITTER: Zheng X 

PROVIDER: S-EPMC11521940 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature