Risk of childhood neoplasms related to neonatal phototherapy- a systematic review and meta-analysis.

ABSTRACT:

Context

Observational studies have shown conflicting results as to whether exposure to neonatal phototherapy is associated with increased rates of childhood cancer.

Objective

To describe the rates of childhood neoplasms and cancer after neonatal phototherapy.

Data sources

The CENTRAL, PubMed, Scopus, and Web of Science databases.

Study selection

Observational studies regardless of design were included.

Data extraction

The data were extracted by one author and validated by another. The risk-of-bias assessment was performed using the ROBINS-E and Joanna Briggs Institute critical appraisal tools.

Results

Six cohort and 10 case-control studies were included. The overall risk of bias was high in seven and low in nine studies. In cohort studies, the odd

SUBMITTER: Kuitunen I 

PROVIDER: S-EPMC11521995 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature