Prognosis After Withdrawal of Cardioprotective Therapy in Patients With Improved Cancer Therapeutics-Related Cardiac Dysfunction.

ABSTRACT:

Background

The long-term prognosis after the discontinuation of cardioprotective therapy (CPT) in patients with cancer therapeutics-related cardiac dysfunction (CTRCD) that has shown improvement remains unclear.

Objectives

This study aims to assess the prognosis after CPT withdrawal in patients exhibiting improved CTRCD.

Methods

In this retrospective analysis of a single-center prospective cohort study, patients with improved CTRCD, defined as an increase in left ventricular ejection fraction (LVEF) ≥10 percentage points from the time of CTRCD diagnosis, were included. We analyzed their clinical outcomes, which included hospitalization for heart failure or a decrease in LVEF ≥10 percentage points within 2 years after CTRCD improvement, alongside echocardiographic chan

SUBMITTER: Park H 

PROVIDER: S-EPMC11522502 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature