Natural history of a newly developed calcified nodule: incidence, predictors, and clinical outcomes.

ABSTRACT:

Background

Calcified nodules (CNs) are an increasingly important, high-risk lesion subset.

Aims

We sought to identify the emergence of new CNs and the relation between underlying plaque characteristics and new CN development.

Methods

Patients who had undergone two optical coherence tomography (OCT) studies that imaged the same untreated calcified lesion at baseline and follow-up were included. New CNs were an accumulation of small calcium fragments at follow-up that were not present at baseline. Cardiac death, myocardial infarction (MI), or clinically driven revascularisation related to OCT-imaged, but untreated, calcified lesions were then evaluated.

Results

Among 372 untreated calcified lesions, with a median of 1.5 (first and third quartiles: 0.7-2.9) years

SUBMITTER: Sugizaki Y 

PROVIDER: S-EPMC11522861 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature