A machine learning algorithm-based risk prediction score for in-hospital/30-day mortality after adult cardiac surgery.

ABSTRACT:

Objectives

A study of the performance of in-hospital/30-day mortality risk prediction models using an alternative machine learning algorithm (XGBoost) in adults undergoing cardiac surgery.

Methods

Retrospective analyses of prospectively routinely collected data on adult patients undergoing cardiac surgery in the UK from January 2012 to March 2019. Data were temporally split 70:30 into training and validation subsets. Independent mortality prediction models were created using sequential backward floating selection starting with 61 variables. Assessments of discrimination, calibration, and clinical utility of the resultant XGBoost model with 23 variables were then conducted.

Results

A total of 224,318 adults underwent cardiac surgery during the study period with a 2.76%

SUBMITTER: Sinha S 

PROVIDER: S-EPMC11522872 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature