In vitro osteogenic and in ovo angiogenic effects of a family of natural origin P₂O₅-free bioactive glasses.

ABSTRACT: Bioactive glasses (BGs) belong to a group of ceramic biomaterials having numerous applications due to their excellent biocompatibility and bioactivity. Depending on their composition, properties of BGs can be finely tuned. In this study, we investigated both angiogenic and osteogenic properties of a novel family of BGs from the SiO₂-CaO-Na₂O system. Three BGs were synthesised from calcite minerals and silica sands extracted from natural deposits. Silica sands used for the synthesis of each glass were obtained from different depths of the deposit, resulting in a different colour and elemental composition. The composition and structural properties of the obtained BGs were determined. Direct culture of human mesenchymal stromal cells (hMSCs) with BG particles at differen

SUBMITTER: Nikody M 

PROVIDER: S-EPMC11523078 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature