VirID: Beyond Virus Discovery-An Integrated Platform for Comprehensive RNA Virus Characterization.

ABSTRACT: RNA viruses exhibit vast phylogenetic diversity and can significantly impact public health and agriculture. However, current bioinformatics tools for viral discovery from metagenomic data frequently generate false positive virus results, overestimate viral diversity, and misclassify virus sequences. Additionally, current tools often fail to determine virus-host associations, which hampers investigation of the potential threat posed by a newly detected virus. To address these issues we developed VirID, a software tool specifically designed for the discovery and characterization of RNA viruses from metagenomic data. The basis of VirID is a comprehensive RNA-dependent RNA polymerase database to enhance a workflow that includes RNA virus discovery, phylogenetic analysis, and phylogeny-based vi

SUBMITTER: Yang Z 

PROVIDER: S-EPMC11523140 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature