High cotinine levels as an associated factor with frailty status in older adults: evidence from the NHANES study.

ABSTRACT:

Introduction

Smoking has been recognized as a contributing factor to frailty in older adults. Nevertheless, it remains uncertain whether the degree of smoking has a discernible impact on frailty among older smokers. This cross-sectional study was conducted to investigate the correlation between serum cotinine levels, a biomarker reflecting tobacco exposure, and the presence of frailty within a nationally representative cohort of older adults.

Method

A total of 1626 individuals aged ≥ 60 who identified as smokers were included in the analysis. Participants were selected based on self-reported current smoking status. According to the Fried Phenotype, frailty is assessed through five dimensions: unintentional weight loss, slow walking speed, weakness, self-reported exhaustion,

SUBMITTER: Xu L 

PROVIDER: S-EPMC11523783 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature