Efficacy and safety of esketamine combined with propofol for conscious sedation in painless colonoscopy: a prospective, randomized, double-blind controlled clinical trial.

ABSTRACT:

Background

We explored the efficacy and safety of esketamine combined with propofol for conscious sedation in painless colonoscopy.

Methods

A total of 195 patients who underwent painless colonoscopy surgery were randomly divided into three groups: the propofol deep sedation group (group DS), the sufentanil combined with propofol for conscious sedation (group CS₁) and the esketamine combined with propofol for conscious sedation (group CS₂). The primary outcomes of this study included the incidence of hypoxemia, hypotension, hypertension, and bradycardia and excellent and good rates of anaesthesia during colonoscopy. The secondary outcomes included perioperative changes in vital signs (MAP, HR, and SpO₂), anaesthesia induction time, dischargeab

SUBMITTER: Xiao L 

PROVIDER: S-EPMC11523800 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature