Association of hemoglobin-to-red blood cell distribution width ratio and bone mineral density in older adults.

ABSTRACT:

Background

Hemoglobin-to-Red Cell Distribution Width Ratio (HRR) represents novel prognostic markers for diseases. However, there remains a lack of systematic research into the relationship between HRR and Bone Mineral Density (BMD) or osteoporosis in older adults.

Methods

This study utilized information from the NHANES database, selecting individuals over 50 years of age with complete femoral DXA scans and full blood counts. The relationship between HRR and femoral BMD was investigated using weighted linear models and restricted cubic spline (RCS) models. Moreover, the association between HRR and osteoporosis was further explored using logistic regression models and RCS models, with subgroup analysis conducted to test the robustness of the results.

Results

This study

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC11523879 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature