Molecular imaging of bacterial biofilms-a systematic review.

ABSTRACT: The formation of bacterial biofilms in the human body and on medical devices is a serious human health concern. Infections related to bacterial biofilms are often chronic and difficult to treat. Detailed information on biofilm formation and composition over time is essential for a fundamental understanding of the underlying mechanisms of biofilm formation and its response to anti-biofilm therapy. However, information on the chemical composition, structural components of biofilms, and molecular interactions regarding metabolism- and communication pathways within the biofilm, such as uptake of administered drugs or inter-bacteria communication, remains elusive. Imaging these molecules and their distribution in the biofilm increases insight into biofilm development, growth, and response to en

SUBMITTER: van Hoogstraten SWG 

PROVIDER: S-EPMC11523921 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature