Ontology highlight
ABSTRACT: Introduction
Alzheimer disease (AD) has a long preclinical phase in which AD pathology is accumulating without detectable clinical symptoms. It is critical to identify participants in this preclinical phase as early as possible since treatment plans may be more effective in this stage. Monitoring for changes in driving behavior, as measured with GPS sensors, has been explored as a low-burden, easy-to-administer method for detecting AD risk. However, driving is a complex, multifaceted process that is likely influenced by other factors, including personality traits, that may change in preclinical AD.Methods
We examine the moderating influence of neuroticism and conscientiousness on longitudinal changes in driving behavior in a sample of 203 clinically normal older adults who
SUBMITTER: Aschenbrenner AJ
PROVIDER: S-EPMC11524437 | biostudies-literature | 2024 Jul-Sep 01
REPOSITORIES: biostudies-literature